Israel says it has delayed Iran's nuclear weapons development "by two or three years."

Israel estimated on Saturday that it had delayed Iran's development of an atomic bomb by "at least two or three years," while Tehran refused to resume negotiations with the United States on its nuclear program if it does not end the Israeli offensive.

The attack launched on June 13 had "very significant" results, Israeli Foreign Minister Gideon Saar told the German newspaper Bild. "We have already delayed the possibility of them having a nuclear bomb by at least two or three years," he said.

"We've already achieved a lot, but we'll do everything we can. We won't stop until we've done everything possible to eliminate this threat," he added.

Israel launched a massive campaign of airstrikes against Iran to prevent its arch-enemy from acquiring the atomic bomb, a goal Tehran denies.

Israeli airstrikes hit hundreds of military and nuclear facilities in the Islamic Republic, which responded with missile and drone launches toward Israel.

According to the latest official Iranian assessment, dated June 15, Israeli airstrikes killed 224 people on Iranian soil, including military commanders, nuclear scientists, and civilians.

The NGO Human Rights Activists News Agency (HRANA), founded in Iran but based in exile in the United States, estimates that the death toll has now reached 657 dead and 2,000 injured.

Iranian retaliatory attacks have reportedly left at least 25 dead in Israel, according to Israeli authorities.

European diplomatic efforts

After more than a week of conflict, in which President Donald Trump is considering involving the United States militarily, European foreign ministers sought a diplomatic solution at a meeting in Geneva on Friday with their Iranian counterparts.

"Iran is willing to reconsider diplomacy once the aggression stops," declared Iranian Foreign Minister Abbas Araqchi.

Although they have not maintained diplomatic relations for four decades, the United States and Iran have held several rounds of negotiations since April regarding Tehran's nuclear program.

The Israeli offensive disrupted these contacts, and now the US president is considering direct intervention in the conflict. Trump declared on Friday that Iran has a "maximum" of two weeks to avoid possible US airstrikes.

On Thursday, he said he would decide on a possible US military intervention in support of Israel "within the next two weeks" because there was a "substantial possibility of negotiations" with Iran.

Republican President Trump also ruled out the success of the diplomatic efforts of Germany, France, the United Kingdom, and the European Union.

For their part, European diplomatic leaders urged Araqchi to continue negotiations "without waiting for the end of the conflict."

French Foreign Minister Jean-Noël Barrot warned that there can be "no definitive military solution to the Iranian nuclear problem."

Before the UN Security Council, the director of the International Atomic Energy Agency (IAEA), Rafael Grossi, stated in his latest report that there is no evidence that Iran is developing an atomic weapon.

Israel is opaque about its arsenal, but the Stockholm International Peace Research Institute (SIPRI) estimates that it has 90 nuclear warheads.

"A prolonged campaign"

Despite these diplomatic maneuvers, the cross-attacks continue.

"We have launched the most complex campaign in our history (...) We must be prepared for a prolonged campaign," warned the Israeli Chief of Staff, Lieutenant General Eyal Zamir, in a video message.

The Israeli military announced on Saturday that it had launched airstrikes "against missile storage and launching facilities in central Iran."

The day before, it attacked various targets in Tehran, Isfahan, and western Iran, and destroyed surface-to-air missile launchers in the southwest.

For their part, the Revolutionary Guards, Iran's ideological army, claimed responsibility for attacks on "military centers, defense industries, command and control centers," and Israeli military bases.

A hospital in Haifa, northern Israel, reported at least 19 people injured by these missiles. Material damage was also reported in the southern city of Beersheba, where another hospital was hit on Thursday.

In Tehran, thousands of people took to the streets on Friday, the country's weekly day of rest, in support of their leaders and in rejection of Israel and the United States, whose flags they burned.

"I will sacrifice my life for my guidance," read a banner, referring to Iranian Supreme Leader Ali Khamenei, who has been threatened in recent days by Israel and its US ally.

Far from the usual Friday bustle, most businesses were closed in Tehran, except for some bakeries and grocery stores.

"I'm not afraid of war. I'm still open, but business is really bad," a shopkeeper who declined to give his name told AFP.