Unusual ingredient that holds the key to breast cancer treatment named

Scientists in Brazil have made a discovery that could change the way breast cancer is treated. Preliminary results of studies have been presented in France, showing that the venom of the Amazon scorpion contains molecules capable of destroying cancer cells.

The increasing incidence of cancer, especially in the context of an aging population and deteriorating environmental conditions, requires the search for new treatment methods. Traditional chemotherapeutic drugs are often accompanied by serious side effects and require the development of more precise and safer agents. In this context, natural compounds such as scorpion venom components represent a promising source of new medicinal molecules.

A group of researchers led by pharmacologist Eliane Candiani Arantes focused on studying the molecules contained in the venom of the Amazon scorpion. During the experiments, the scientists identified a special molecule that resembles similar compounds from the venom of other scorpions in structure and action. This molecule, obtained using genetic engineering, is capable of triggering the process of necrosis - programmed cell death - in breast cancer cells.

The resulting molecule, called BamazScplp1, causes the cell membrane of cancer cells to rupture, causing them to die. This mechanism is similar to the action of some chemotherapeutic drugs, but due to its natural origin, the molecule may have less toxicity and a more precise effect.

In addition, scientists have discovered another molecule that promotes the growth of blood vessels - a growth factor made from components of snake venom and cattle blood. This factor may play a dual role: on the one hand, it promotes tumor development, and on the other, it can be used to create new methods of drug delivery or for regenerative purposes.

To produce the molecules of interest on a large scale, scientists use heterologous expression, a technology in which genes encoding the desired proteins are introduced into other organisms, such as yeast. This approach allows them to obtain large volumes of biologically active substances, study their functions, and create mutations to improve their effectiveness.

The use of genetic engineering opens up new possibilities for the search for and development of drugs based on natural compounds that previously remained inaccessible for mass production.

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