2025 Goodyear 400 odds, Darlington NASCAR picks: Expert who hit 17 winners loving 50-1 longshot

Denny Hamlin is off to a solid start to his 2025 season and will eye back-to-back wins on Sunday at the 2025 NASCAR Cup Goodyear 400 at Darlington Raceway. Hamlin grabbed the lead on lap 126 last week and never looked back, earning his first win of the season at the Cook Out 400 at Martinsville Speedway. It was Hamlin's sixth win at the track, the most among full-time active drivers but his first at Martinsville since 2015. It was also his 55th win of his 20-year career.

Kyle Larson is the favorite at +500, with William Byron at +650, Tyler Reddick at +650, Ryan Blaney and Hamlin at +700, and Christopher Bell at +1000 in the latest 2025 Goodyear 400 at Darlington Raceway odds. Byron will be on the pole, and Sunday's race is scheduled to start at 3 p.m. ET. Before making any 2025 Goodyear 400 at Darlington Raceway picks or NASCAR predictions, you need to see what NASCAR insider Steven Taranto has to say.

Taranto, who moonlights as a sim racer and has 20 career wins in iRacing, is the lead NASCAR writer for CBSSports.com and chronicles stock car racing with the same thoroughness and passion he's had since becoming a full-time race fan in 2001. He has an annual NASCAR medial credential and also publishes a popular weekly NASCAR predictions column, famously calling Ross Chastain and Daniel Suarez's breakthrough wins in 2022.

Taranto was red-hot for SportsLine in 2024 as he nailed 17 winners, including 16-1 longshot William Byron at the Daytona 500 and 14-1 longshot Chase Elliott at Texas. He correctly picked the Straight Talk Wireless 400 winner in Larson on March 23. Anyone following his NASCAR picks at their favorite sportsbooks could have seen huge returns.

Now, Taranto has analyzed the starting lineup and odds for Sunday's 2025 NASCAR Cup Goodyear 400 at Darlington Raceway. He's sharing his best bets at SportsLine.

2025 Darlington NASCAR expert picks

For the 2025 Goodyear 400 at Darlington Raceway, Taranto is high on Kyle Larson, who has fared well at Darlington. He has led for 1,048 laps in his career at the track, including 278 in his last four starts there. In his last race there, the 2024 Cook Out Southern 500, he led for most of the race before settling for fourth place. He won the 2023 Cook Out Southern 500. Larson is going off at +450 at DraftKings.

The 32-year-old Hendrick Motorsports veteran has registered 30 career Cup Series wins, registering 21 poles and 187 top-10 finishes in 372 races over 13 years. He won the 2021 season championship, and placed sixth overall in 2024. He registered his first win at 2016 Pure Michigan 400. He has also had success in the NASCAR Xfinity Series, earning 15 wins, 83 top-10 finishes and seven poles over a 10-year span. See which other drivers he's backing at SportsLine.

Goodyear 400 prop picks

Head-to-head, Taranto sees Bubba Wallace (-125) finishing ahead of Chase Elliott (-110). Wallace has had success at Darlington and won the pole for last September's Southern 500. Wallace has three top-10 finishes this season, including back-to-back third-place finishes. In 255 career Cup Series races, Wallace has two wins, three poles and 49 top-10 finishes over an eight-year span.

Elliott, meanwhile, has had four top-10 finishes, and finished in the top 20 in all seven Cup races in 2025. Elliott is looking to win for the first time since winning the 2024 Autotrader EchoPark Automotive 400 at Texas Motor Speedway. He placed fourth last week at the Cook Out 400 at Martinsville. In his 10-year career, he has posted 19 wins and 174 top-10 finishes. See all of Taranto's picks at SportsLine.

How to make 2025 Goodyear 400 predictions

Taranto has also identified four other drivers in his 2025 NASCAR Goodyear 400 best bets. He's also high on a huge NASCAR longshot who's going off at over 50-1, potentially netting any backer a huge payday. You can only see who they are here.

So who wins the 2025 Goodyear 400 at Darlington, and which massive longshot could stun NASCAR? Visit SportsLine now to see the 2025 Goodyear 400 at Darlington picks and best bets from a NASCAR insider who nailed a colossal 17 winners last year, and find out.

2025 Goodyear 400 at Darlington Raceway odds, lineup

See full Goodyear 400 at Darlington Raceway picks at SportsLine

Kyle Larson +500 Tyler Reddick +650William Byron +650 Ryan Blaney +700 Denny Hamlin +700 Christopher Bell +1000 Joey Logano +1500 Chase Briscoe +1500 Bubba Wallace +1600 Ross Chastain +1800 Kyle Busch +1800 Chase Elliott +1800 Chris Buescher +2200 Brad Keselowski +2800 Alex Bowman +3000 Josh Berry +3500 Austin Cindric +4000 Ty Gibbs +5000 Noah Gragson +5000 Erik Jones +5000 Ryan Preece +5500 Carson Hocevar +6500 A.J. Allmendinger +6500 Daniel Suarez +10000 Michael McDowell +17000 Zane Smith +20000 Todd Gilliland +20000 Ricky Stenhouse Jr. +20000 Justin Haley +20000 Austin Hill +20000 Austin Dillon +20000 Riley Herbst +25000 Cole Custer +25000 Shane Van Gisbergen +30000 John Hunter Nemechek +30000 Ty Dillon +50000 J.J. Yeley +100000 Cody Ware +100000